Game time too long?
Solution: Quick Play w/Quick Counts (Takes me on avg 35 minutes a game)
Season too long?
Solution: Choose one pitcher on your team, and play all of their starts (Approx 32 starts), and then if you come to a series where you starting pitcher doesn't start, choose one of the games and play (Approx 30-40 games) and then simulate the rest.
Roster Size too big?
Solution: Just gotta deal with it