Quote:
Originally Posted by Izulde
I'm sorry to hear this, Lorena. Those dosage amounts sound awfully high IMO.
As a bipolar myself who has stopped his medication numerous times (in fact it's been a year, year and a half maybe since I've taken it), I can say that getting us to stay on our medications is one of the biggest battles, both for us and those who care about us.
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Speaking in generalities and not about any specific person, 500 mg of Depakote is not a large dosage. In fact, it is the starting dosage for most adults. A typical daily dosage for a person who has classic Bipolar (or even someone who has organic damage that is mimicking Bipolar) is 1000-2000 mg depending upon their body mass, etc. However, if they are elderly and/or have decreased Liver functions they may need a smaller dosage. Similarly, 300 mg of Seroquel is not a large dosage for someone who is really manic and/or psychotic. A typical target dosage of Seroquel is often 600-800 mg unless a person has impaired clearance.
Edit to clarify: I'm talking about total dosage per day in the above numbers. Depakote is often giving divided 2-4 times/day (500 mg, 3 times per day is not uncommon for an adult) while Seroquel is often given twice a day.
I agree with your 2nd point completely. Compliance with medications is the biggest issue for most people with Bipolar and many patients end up being hospitalized 4-5 times before their compliance increases.
Anyway, I'll be keeping your family in my prayers, DC.