Steve from OS has posted answers to another batch of questions:
http://www.operationsports.com/preview.php?id=37
Here is an excerpt of the question I asked and the answer (he hasn't adjusted sliders at all, yet.):
eaglesfan27: Steve,
Yesterday, you mentioned that you had only seen 1 pick 6 (unless I misunderstood your answer). On average, how many CPU thrown interceptions are you seeing per game?
Thanks for taking the time to do this.
Steve: AI has thrown, on average, 2 INT's per game. I've seen as many as 4 in 7 min. qtrs and I've actually seen a game where the AI didn't throw a single pick. So far in my time of playing, I've seen 2 pick 6's now. TONS better than last year, as the AI throwing picks in general was extremely annoying.
Also, he posted screenshots of stats from a full simulated season:
http://www.operationsports.com/mediaview.php?id=417
From looking at the screenshots:
QB Ratings seem a bit high for the leaders, maybe due to high completion percentages, but in the further screenshots their are QB's throwing a good number of INT's (20 in one screenshot for a QB who threw it a lot and was one of the leaders in yardage.) Yardage totals look good. Another screenshot shows that the highest Interception totals were: 27 (with 20 TD's), 20, several guys with 17, 16, and 15. About a half dozen to a dozen guys with over 70% completion rates with the highest at 73%.
Leading rusher had 1865 yards on the year with 19 TD's. Lots more screenshots up on OS, but the stats generally look good.