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-   -   COVID-19 - Wuhan Coronavirus (a non-political thread, see pg. 36 #1778) (https://forums.operationsports.com/fofc//showthread.php?t=96561)

albionmoonlight 04-29-2020 10:53 AM

I think this can be here and not the political thread, but I wonder how much our reaction to the virus has been molded by our short attention spans.

When this started, everyone agreed that we would need a few months of social distancing to really get a handle on things. And that we would not be "normal" until we got a vaccine in 12-18 months.

2 weeks into that, and you have a lot of people all saying "Well, we did that. Now everyone pretend that everything is normal again."

I don't know if it is a Right/Left thing so much as a no one has patience to do anything anymore thing.

sterlingice 04-29-2020 11:42 AM

Quote:

Originally Posted by albionmoonlight (Post 3278239)
I think this can be here and not the political thread, but I wonder how much our reaction to the virus has been molded by our short attention spans.

When this started, everyone agreed that we would need a few months of social distancing to really get a handle on things. And that we would not be "normal" until we got a vaccine in 12-18 months.

2 weeks into that, and you have a lot of people all saying "Well, we did that. Now everyone pretend that everything is normal again."

I don't know if it is a Right/Left thing so much as a no one has patience to do anything anymore thing.


The last few years has made me think that, generally, as a society, we're kindof screwed.

SI

Atocep 04-29-2020 12:15 PM

Quote:

Originally Posted by albionmoonlight (Post 3278239)
I think this can be here and not the political thread, but I wonder how much our reaction to the virus has been molded by our short attention spans.

When this started, everyone agreed that we would need a few months of social distancing to really get a handle on things. And that we would not be "normal" until we got a vaccine in 12-18 months.

2 weeks into that, and you have a lot of people all saying "Well, we did that. Now everyone pretend that everything is normal again."

I don't know if it is a Right/Left thing so much as a no one has patience to do anything anymore thing.



Even in my neighborhood, which as been one of the best in this area at adhering to guidelines, things as simple as the single direction aisles at safeway are breaking down and social distancing is becoming isn't being followed as strictly as it was even a couple of weeks ago.

IMO we as humans have a difficult time watching others break rules or guidelines with no perceived punishment before we decide to do the same ourselves.

bhlloy 04-29-2020 12:15 PM

Quote:

Originally Posted by albionmoonlight (Post 3278239)
I don't know if it is a Right/Left thing so much as a no one has patience to do anything anymore thing.


A couple of anecdotal stories from this weekend to support the thought that people are just done with the lockdown - there were at least 3/4 pool parties with screaming kids, loud music and cars all over the street we saw/heard this weekend while walking our dogs, and talking to an old coworker who is doing bike rides down PCH he said the beaches on Sunday were pretty packed. And this is LA, so it's certainly not a taking shots at Red states thing.

I think human nature is to not going to accept being cooped up in isolation for months on end, consequences be damned. I don't necessarily agree with it, but we are where we are, and I'm not sure it would have been massively different at any time in human history to be honest other than the fact that we have the technology and the connectivity to be able to instantly analyze and judge it today.

Atocep 04-29-2020 02:25 PM

Quote:

Originally Posted by Lathum (Post 3278007)
I asked about accuracy. He said it is a blood test and very accurate. We all showed some symptoms a while back and what we thought was the flu ripped through our kids school in January. We live in a hot zone and it would just be nice to know. He also said insurance should cover it, but if it doesn't the government should. TBH I would pay OOP within reason to know.


https://www.nbcnews.com/politics/con...tests-n1194876

It seems that as of right now they're not all that accurate and results vary depending on who made the test.

whomario 04-29-2020 02:26 PM

Good news, bad news time ...

Bad:

Christian Drosten on Twitter: "Viral loads by PCR as seen in our laboratories. No significant difference between children and adults. Age categories: Kindergarten (KG), Grade school (GS), Highschool (HS), etc. with age ranges and (counts). https://t.co/xunzyHEi47… https://t.co/xdURZBqqto"

Basically: while absolutely less kids get symptoms* (hence less tests to analyze), they shed similar amounts of virus as a group.

* We just don't know how often they get infected in the first place (maybe there is some Background 'immunity') because they don't get sick so rarely tested in the first place and all antibody studies either ignore them by design or did not differentiate them in the results. Or like a german one sits on the results to finish the paper ... Which is insanely frustrating considering how urgen people need to know how to handle schools and daycare etc.


https://www.nytimes.com/2020/04/27/w...e=articleShare

New earliest "if all the stars align" date for first production of a vaccine in September.

Would be pretty cool if a smallish university lab comes through first against the odds.

Brian Swartz 04-29-2020 03:31 PM

Seems that while NY is gradually getting better, the rest of the nation is picking up the slack. Pennsylvania and Illinois particularly of late.

henry296 04-29-2020 03:39 PM

Quote:

Originally Posted by Brian Swartz (Post 3278323)
Seems that while NY is gradually getting better, the rest of the nation is picking up the slack. Pennsylvania and Illinois particularly of late.


The PA numbers may be a reporting catch-up. Today's press release states 479 new reported deaths which happened over the past 2 weeks. Here is the exact quote:

As a result of our continued work to reconcile data from various sources, the state is reporting an increase of 479 deaths today bringing the statewide total to 2,195 deaths in Pennsylvania. These deaths have occurred over the last two weeks.

Also 2/3 of PA deaths are in nursing homes, so it is concentrated to those types of specific outbreaks that social distancing likely doesn't mitigate well.

miked 04-29-2020 03:58 PM

Does the UK really have 4500 today?

RainMaker 04-29-2020 04:07 PM

Kind of an interesting idea out of New York for restaurants. Close down some streets and let the restaurants set up outdoor seating in them. Allows for proper social distancing, fresh air, and keeping those restaurants open. I like it.

Coronavirus in NYC: Restaurant Reopening Could Include Seats on Closed Streets - Eater NY

bhlloy 04-29-2020 04:11 PM

Quote:

Originally Posted by miked (Post 3278333)
Does the UK really have 4500 today?


No, they included care home deaths in the numbers for the first time today

Lathum 04-29-2020 04:17 PM

I think the key to Instacart is doing the fast and flexible. I got wind they may strike on 5/1 and I had a delivery set for 5/2. I changed it today to fast and flexible for today or tomorrow and it showed up within 2 hours. I even got a huge bottle of hand sanitizer.

RainMaker 04-29-2020 04:20 PM

Quote:

Originally Posted by Brian Swartz (Post 3278323)
Seems that while NY is gradually getting better, the rest of the nation is picking up the slack. Pennsylvania and Illinois particularly of late.


Ohio had its highest death total day and they are opening up on Friday.

NobodyHere 04-29-2020 04:27 PM

Quote:

Originally Posted by RainMaker (Post 3278347)
...and they are opening up on Friday.


That's a bit of a hyperbolic way of putting it.

A few business types are being allowed to reopen and they have restrictions. So it's not like business as usual.

sterlingice 04-29-2020 07:50 PM

On the other hand, Texas is pretty much opening the doors Friday

SI

panerd 04-29-2020 08:42 PM

I generally find my views on this board tend to lean to the right of most of you guys even though in real life I'm hardly Republican but I totally agree that they are loosening these restrictions a little too early. Anecdotal of course but I remember back when St. Louis had a pending stay at home that was clearly coming and some friends decided to get a "last hurrah" in that didn't make any sense at all. I mean the highly contagious disease is out there, hence the stay at home order that was coming. So I totally agree in the next couple of weeks that those same people are going to overdo it.

Here's where I differ a little with you guys and differ a lot more with social media/local paper comment section etc... These idiots who do go out right away are really just exposing themselves to risk, getting sick. The whole point of any of this was to flatten the curve and I think we did that almost everywhere and now (IMO obviously) I think the hospitals will not be overrun in the summer for lots of reasons. (Hotter/humid, people more aware, a lot of people have had this (again IMO), masks and social distancing a little more understood etc) There is no blood on hands, these people are not killing other people etc. Sorry but 60,000 people didn't die because of anything but a deadly virus not everything has to be political. (I saw one guy on social media blame every single death on political decisions like had we done something different there would have been zero deaths here even though the rest of the world clearly got hit) I think that hyperbole is sadly what is causing people to want to open businesses too early.

IlliniCub 04-29-2020 08:49 PM

Quote:

Originally Posted by Brian Swartz (Post 3278323)
Seems that while NY is gradually getting better, the rest of the nation is picking up the slack. Pennsylvania and Illinois particularly of late.

Interesting thing about Illinois numbers, we ramped up testing capacity by a great deal went from 5000 to over 15000 a day. Total amount of daily cases increased but the percentage of positive tests decreased. So I still think Illinois is improving, hopefully.

Edward64 04-29-2020 09:22 PM

Worldometers reporting 2,390 so it has gone back up from the mid 1K to mid 2K. It's not NY and NJ anymore but other states making up the difference.

The lack of recent news on respirators I think (probably) means there is sufficient supply now. No more news on hospital bed capacity and building field hospitals so assume that means the same.

I sure hope the Gilead drug proves real.

RainMaker 04-29-2020 11:02 PM

Pennsylvania had a big jump so I am wondering if they just had a backlog that is making the number seem higher today.

Then again there are likely states playing games with the numbers.

https://www.tampabay.com/news/health...ade-them-stop/

Chief Rum 04-30-2020 12:11 AM

Quote:

Originally Posted by RainMaker (Post 3278512)
Pennsylvania had a big jump so I am wondering if they just had a backlog that is making the number seem higher today.

Then again there are likely states playing games with the numbers.

https://www.tampabay.com/news/health...ade-them-stop/


From up thread.

Quote:

Originally Posted by henry296 (Post 3278325)
The PA numbers may be a reporting catch-up. Today's press release states 479 new reported deaths which happened over the past 2 weeks. Here is the exact quote:

As a result of our continued work to reconcile data from various sources, the state is reporting an increase of 479 deaths today bringing the statewide total to 2,195 deaths in Pennsylvania. These deaths have occurred over the last two weeks.

Also 2/3 of PA deaths are in nursing homes, so it is concentrated to those types of specific outbreaks that social distancing likely doesn't mitigate well.


whomario 04-30-2020 03:50 AM

Quote:

Originally Posted by henry296 (Post 3278325)

Also 2/3 of PA deaths are in nursing homes, so it is concentrated to those types of specific outbreaks that social distancing likely doesn't mitigate well.


Aside from me thinking the 2/3 is bogus and a sign they missed a lot of at-home deaths etc:
That is my absolute pet peeve ... I know how you mean it and see what you are getting it, so please don't take this personally ;)

More infections in the general populus inevitably lead to more outbreaks in closed-off systems. There will always be cracks in the wall and the more infected are walking around, the more likely it is those are exposed (the most obvious one being that more Infections generally obviously increases the risk that any given nurse or administrator working in a home infects themselves in the outside world).

You need to do all you can to close the cracks or mitigate the outfall of any given outbreak (germany is currently testing every nurse, administrator and inhabitant of all homes and all ambulatory providers as well, planning to repeat this every 3-4 weeks), but that is going to be infinitely easier with a low infection rate in the general public.

QuikSand 04-30-2020 04:10 AM

The debate over COVID death count will never settle. It is already devolving into red/blue territory, and that's like a black hole for rationality.

We're seeing multiple credible studies look at "deaths over expected levels," and I have yet to hear any explanation for why those numbers should be so much larger than the reported COVID death counts. However, because those point in a direction that could be politically damaging for the incumbent administration, the two sides immediately rush to weaponize/discredit the line of thinking, without any regard to the math, science, or medicine behind it.

And, to be fair, I cannot really tell if I'm just a victim of the same hatred. I am not really qualified to assess the validity of the argument, but is the reason why I find it superficially compelling is that it seems like it might increase the percentage chance that Trump leaves office soon? I mean - that is basically all I care about in pure politics right now, so maybe I'm every bit as deranged by my own biases as everyone else I'm criticizing.

CrimsonFox 04-30-2020 04:24 AM

Well it is indeed true that they did not count those in nursing homes or those found dead in the count. And by and by some governors started reporting "probable death by covid" to be a trackable datapoint. But some won't. That's a given. Florida numbers seem unreliable now too.
always florida...

Edward64 04-30-2020 06:44 AM

Definitely the right thing to do.

Bloomberg - Are you a robot?
Quote:

The Trump administration is organizing a Manhattan Project-style effort to drastically cut the time needed to develop a coronavirus vaccine, with a goal of making enough doses for most Americans by year’s end.

Called “Operation Warp Speed,” the program will pull together private pharmaceutical companies, government agencies and the military to try to cut the development time for a vaccine by as much as eight months, according to two people familiar with the matter.

As part of the arrangement, taxpayers will shoulder much of the financial risk that vaccine candidates may fail, instead of drug companies.

The project’s goal is to have 300 million doses of vaccine available by January, according to one administration official. There is no precedent for such rapid development of a vaccine.

Per the project cost and "significant waste", I think most will understand and still support this.

As a side note, I wonder what PETA's response would be on the animal experiments.

Quote:

Vaccine development is typically slow and high risk. The project’s goal is to cut out the slow part, the people said. Operation Warp Speed will use government resources to quickly test the world’s most promising experimental vaccines in animals, then launch coordinated human clinical trials to winnow down the candidates.
:
:
The project will cost billions of dollars, one of the people said. And it will almost certainly result in significant waste by making inoculations at scale before knowing if they’ll be safe and effective -- meaning that vaccines that fail will be useless. But it could mean having doses of vaccine available for the American public by the end of this year, instead of by next summer.
:
:
The group is also discussing the use of what’s known as a master protocol to test the vaccines. Instead of multiple clinical trials run by each drugmaker, competing for patients and resources, the government would organize one large trial to test several vaccines at once and advance the most promising ones.

panerd 04-30-2020 08:00 AM

Quote:

Originally Posted by QuikSand (Post 3278541)
The debate over COVID death count will never settle. It is already devolving into red/blue territory, and that's like a black hole for rationality.

We're seeing multiple credible studies look at "deaths over expected levels," and I have yet to hear any explanation for why those numbers should be so much larger than the reported COVID death counts. However, because those point in a direction that could be politically damaging for the incumbent administration, the two sides immediately rush to weaponize/discredit the line of thinking, without any regard to the math, science, or medicine behind it.

And, to be fair, I cannot really tell if I'm just a victim of the same hatred. I am not really qualified to assess the validity of the argument, but is the reason why I find it superficially compelling is that it seems like it might increase the percentage chance that Trump leaves office soon? I mean - that is basically all I care about in pure politics right now, so maybe I'm every bit as deranged by my own biases as everyone else I'm criticizing.


I live in Eureka, MO which will at a minimum has already become the center of a major local/state news story in the last week or so and possibly elevate to national story here soon.

Eureka bucks St. Louis County order, says it will reopen on Monday | Local Business | stltoday.com

The thing about it is I know a lot of the principal actors involved (the mayor, some of these business owners) and they are all good people who are seriously misinformed and have taken the Red/Blue thing like you said to a whole new level. It's really sad because here's my synopsis of what happened and what could have happened to avoid any of this...

1) My hometown is divided between two counties (St Louis and Jefferson) one of which is under a county stay at home and the other whose statewide stay at home order will end next week.

2) The mayor has decided he is siding with the state as our city (approx 10K) is definitely more rural than St Louis City and even a lot of it's municipalities.

3) IMO the locals are wrong here not only in underestimating the virus but also understanding the law and the county's authority.

4) However they are fueled by social media/St Louis paper etc where they are basically framing the town as a bunch of redneck "deplorables".

I have no good thoughts on how this will likely end but sort of see this for the entire country. We are not in a good place, not everything is Red/Blue and there are decent/good and shitty/evil people on both sides. I'm not sure if this country is going to make it. Unfortunately the end result is either a lot of people die or it is possible that a lot of people won't die in more rural spread out area. Both would be counted as "wins" right? God it's depressing.

whomario 04-30-2020 08:12 AM

Quote:

Originally Posted by Edward64 (Post 3278554)
Definitely the right thing to do.

Bloomberg - Are you a robot?


Per the project cost and "significant waste", I think most will understand and still support this.



Good of them to join the party and waking up to what is needed.
Ideally you really do need to do parallel production of as many promising candidates as possible before they have been proven in studies and then have it ready to go once it is proven. More costly but also safer than cutting to many corners in testing and ending up betting on the wrong horse ...
Basically what Bill Gates was planning/proposing makes a lot of sense.

This will happen all over the globe and actually already is. A very large vaccine producer in india (one of the worlds largest or the largest, can't quite remember) is already starting production on the Oxford vaccine i linked yesterday before this trial has even started on the off-chance this turns out great and then you at least have the first few million avaialable for a large scale global study.

Galaril 04-30-2020 09:09 AM

The cut corners and speeding up vaccine dev and creation was what I had hoped for. I am not super happy about tax payers shouldering the financial burden, but big Pharma is only about the benjamins. Now I go back to a question I asked especially in light of the sped up vaccine process. Are people ready to get a vaccine right away based on what their government saying it is safe?Though I am not an anti vacciner I have zero trust in the US leadership. I seem to remember zombie apocalypse or the planet of the apes scenario occurring due to a screwed up vaccine for something in movies. We probably have no choice but cross our fingers and role up our sleeves for the needle but it still all now gives me pause.
Also, if it is unclear or proven there is not an immunity for people who have had it would we make the vaccine mandatory for all citizens?

panerd 04-30-2020 09:14 AM

Quote:

Originally Posted by Galaril (Post 3278578)
Also, if it is unclear or proven there is not an immunity for people who have had it would we make the vaccine mandatory for all citizens?


I thought that was basically what a vaccine worked off of. I mean if the antibodies do nothing there cant be a vaccine right?

miami_fan 04-30-2020 09:14 AM

Quote:

Originally Posted by panerd (Post 3278419)
I generally find my views on this board tend to lean to the right of most of you guys even though in real life I'm hardly Republican but I totally agree that they are loosening these restrictions a little too early. Anecdotal of course but I remember back when St. Louis had a pending stay at home that was clearly coming and some friends decided to get a "last hurrah" in that didn't make any sense at all. I mean the highly contagious disease is out there, hence the stay at home order that was coming. So I totally agree in the next couple of weeks that those same people are going to overdo it.

Here's where I differ a little with you guys and differ a lot more with social media/local paper comment section etc... These idiots who do go out right away are really just exposing themselves to risk, getting sick. The whole point of any of this was to flatten the curve and I think we did that almost everywhere and now (IMO obviously) I think the hospitals will not be overrun in the summer for lots of reasons. (Hotter/humid, people more aware, a lot of people have had this (again IMO), masks and social distancing a little more understood etc) There is no blood on hands, these people are not killing other people etc. Sorry but 60,000 people didn't die because of anything but a deadly virus not everything has to be political. (I saw one guy on social media blame every single death on political decisions like had we done something different there would have been zero deaths here even though the rest of the world clearly got hit) I think that hyperbole is sadly what is causing people to want to open businesses too early.


I agree with you for the most part. From what I have seen so far, most of the plans seem to be reasonable. I still believe it is too early but at this point I would only be delaying the current plans by 2 weeks or so.. I am going to sound like a broken record but for me it all goes back to trust. It also touches on what I feel is the pettiness (IMO) that you seem to allude to in your last sentence.

I would be in 100% agreement with you if I trusted that people would act on being more aware, masks, and social distancing. The problem would be if (because I am trying to give the benefit of the doubt) people are, at best not aware of those things or at worst are aware but don't give a damn because "that is their right" or because of the hyperbole that they have see. I have a hard time believing in the existence in the not aware but if they do exist then that is a societal fail and we need to do better with education. Then we get to the don't give a damn crowd.

We are already seeing the rebellion about being "forced" to wear the masks and having to adhere to one way aisles in stores begin. I assume those people are similar to the people you talked about who went out for the last hurrah. Yes, they may have learned the lesson during the stay at home time but we can't ignore that this was a thing before and for some is a thing now. I have no idea what percentage of people that is but there is a percentage of people who are going to do that again. What I don't understand is why it is wrong to acknowledge that, for a portion of the population, not giving a damn about those precautions that you mentioned is a political statement. Especially when those same people are telling you they are doing it as a political statement. The old saying "When someone shows you who they are, believe them." seems appropriate in this case.

Whether I believe it is the right time or not, reopening is happening. Everyone has acknowledged that in order for the reopening to work, there are still precautions that need to be taken. If people are actively and purposefully not engaging in those precautions, they should be acknowledged such. Do I need to take it as far as having blood on their hands? No, but this seems like complaining about the use of the term soldier in the sports world IMO. If I have the flu (yes I know, but I am not trying to be cheeky here) and I purposefully go into an office setting while sick, that is a decision I made that could affect other people. If others get sick after me in the office, it is acknowledged that I got them sick. The reality is it is possible they could have gotten it from anybody else they came in contact with who has the flu, but given that scenario I get the blame. That has been the way of the world since I have been alive. I am not sure why it would be different with CV?

ISiddiqui 04-30-2020 09:29 AM

Quote:

Originally Posted by Edward64 (Post 3278554)
Definitely the right thing to do.

Bloomberg - Are you a robot?


I like it, though Operation Warp Speed is a super silly name (though most 'Operations' are a little weirdly named - however, Operation Desert Storm was a really cool name).

ISiddiqui 04-30-2020 09:32 AM

Quote:

Originally Posted by panerd (Post 3278567)
1) My hometown is divided between two counties (St Louis and Jefferson) one of which is under a county stay at home and the other whose statewide stay at home order will end next week.


The worst part is that you know a bunch of people from St. Louis County are going to stream into Jefferson County, and then bring that back into their county. Which is just going to make things worse.

panerd 04-30-2020 09:40 AM

Quote:

Originally Posted by ISiddiqui (Post 3278585)
The worst part is that you know a bunch of people from St. Louis County are going to stream into Jefferson County, and then bring that back into their county. Which is just going to make things worse.


Yeah that kind of has always been the gist of St. Louis being on the Illinois/Missouri border with the vast difference in red state/blue state. People have always crossed to Illinois for vices (pot, strip clubs, Sunday liquor, horse racing, casino gambling back in the 90's) and crossed into Missouri for the more lax laws, lower taxes. But yeah now it's a virus that doesn't understand man-made boundaries.

Sadly I am most scared about people making a big show about how everything is fine. So instead of actually going to a restaurant and not sitting within 6 feet, wearing a mask in stores, and probably not getting sick they will flaunt all those rules and make it worse for everyone. Like the California beaches our parks keep opening and closing because people can't follow simple guidelines. I mean think just one 3 mile trail (what 15000 ft?) how you could actually have thousands of people socially distancing. Instead they congregate in parking lots and hang out and get them shut down again for the rest of us.

panerd 04-30-2020 09:47 AM

Quote:

Originally Posted by miami_fan (Post 3278581)
I agree with you for the most part. From what I have seen so far, most of the plans seem to be reasonable. I still believe it is too early but at this point I would only be delaying the current plans by 2 weeks or so.. I am going to sound like a broken record but for me it all goes back to trust. It also touches on what I feel is the pettiness (IMO) that you seem to allude to in your last sentence.

I would be in 100% agreement with you if I trusted that people would act on being more aware, masks, and social distancing. The problem would be if (because I am trying to give the benefit of the doubt) people are, at best not aware of those things or at worst are aware but don't give a damn because "that is their right" or because of the hyperbole that they have see. I have a hard time believing in the existence in the not aware but if they do exist then that is a societal fail and we need to do better with education. Then we get to the don't give a damn crowd.

We are already seeing the rebellion about being "forced" to wear the masks and having to adhere to one way aisles in stores begin. I assume those people are similar to the people you talked about who went out for the last hurrah. Yes, they may have learned the lesson during the stay at home time but we can't ignore that this was a thing before and for some is a thing now. I have no idea what percentage of people that is but there is a percentage of people who are going to do that again. What I don't understand is why it is wrong to acknowledge that, for a portion of the population, not giving a damn about those precautions that you mentioned is a political statement. Especially when those same people are telling you they are doing it as a political statement. The old saying "When someone shows you who they are, believe them." seems appropriate in this case.

Whether I believe it is the right time or not, reopening is happening. Everyone has acknowledged that in order for the reopening to work, there are still precautions that need to be taken. If people are actively and purposefully not engaging in those precautions, they should be acknowledged such. Do I need to take it as far as having blood on their hands? No, but this seems like complaining about the use of the term soldier in the sports world IMO. If I have the flu (yes I know, but I am not trying to be cheeky here) and I purposefully go into an office setting while sick, that is a decision I made that could affect other people. If others get sick after me in the office, it is acknowledged that I got them sick. The reality is it is possible they could have gotten it from anybody else they came in contact with who has the flu, but given that scenario I get the blame. That has been the way of the world since I have been alive. I am not sure why it would be different with CV?


Yep and that is the rub. It's kind of like talking about pot with teenagers. (Bear with me a little as I know its a contagious virus and this analogy is a bit out there)

Should 14 year olds be smoking pot? No. Are there serious health consequences and life destroying choices being made? Absolutely. So let's say there are 3 camps...

1) Don't smoke. You will eventually go on to harder drugs and die.

2) Some sort of nuanced approach that acknowledges kids make bad decisions etc but educates them on bad choices and even more dangerous drugs.

3) Do whatever you want.

Somehow this virus debate seems to be between 1 and 3 doesn't it?

ISiddiqui 04-30-2020 10:17 AM

Quote:

Originally Posted by panerd (Post 3278588)
Like the California beaches our parks keep opening and closing because people can't follow simple guidelines. I mean think just one 3 mile trail (what 15000 ft?) how you could actually have thousands of people socially distancing. Instead they congregate in parking lots and hang out and get them shut down again for the rest of us.


You know the meme "This is why we can't have nice things"? I simply can't understand how people just completely fuck it up for everyone else because they can't follow simple guidelines. This is what gives me pause for the gradual reopening, because once you give a crack, people stream through like it's business as usual.

So I get the arguments that flattening the curve means not overwhelming hospitals and in a lot of areas that looks like it happened, but that only works if people keep socially distancing and being smart when certain things are reopened. If they just act like pre-pandemic, the curve is right back un-flattened.

Sometimes we can be so individualistic that it drives me mad - think about your fellow neighbors!

Castlerock 04-30-2020 10:36 AM

Quote:

A new online tool, COVID-19 Simulator, developed by researchers at Massachusetts General Hospital (MGH) and Georgia Tech can help policy makers see how lifting or extending different social-distancing measures at various times can impact each state in terms of COVID-19 cases, hospitalizations, and deaths. The tool uses most recent data for each state and infectious disease modeling, as recommended by expert epidemiologists.

Home - COVID-19 Simulator

This shows what the experts have been saying about what happens after we relax restrictions.

miami_fan 04-30-2020 10:43 AM

Quote:

Originally Posted by panerd (Post 3278589)
Yep and that is the rub. It's kind of like talking about pot with teenagers. (Bear with me a little as I know its a contagious virus and this analogy is a bit out there)

Should 14 year olds be smoking pot? No. Are there serious health consequences and life destroying choices being made? Absolutely. So let's say there are 3 camps...

1) Don't smoke. You will eventually go on to harder drugs and die.

2) Some sort of nuanced approach that acknowledges kids make bad decisions etc but educates them on bad choices and even more dangerous drugs.

3) Do whatever you want.

Somehow this virus debate seems to be between 1 and 3 doesn't it?


Actually that example is perfect.

I generally push back against it not being a Red/Blue issue at all. None of this is in a vacuum. We have had to make these types of choices before. In general, if we have a choice between 1,2,and 3, we generally choose 1 if it has even the potential to hurt themselves and others (i.e. health risks) or definitely has the potential to hurt others (i.e enjoyment of). We also severely punish anyone who goes against option 1 or choose the harder stuff. If we ever choose option 3, it is in a limited context i.e. our kids over here can do whatever they want as opposed to THOSE kids over here.

Option 2 today means you are wishy washy and unwilling to take a stand.

EDIT: Just to clarify, if our recent choice history was 2 or 3, we would not have nearly the divide. IMO. We have made different choices in the past and I wonder why we are making the choices we are making now.

Galaril 04-30-2020 11:48 AM

I am not sure if this is the best place for this but this is a very interesting take on how the virus will change travel in all sorts of interesting and very plausible ways. For example this quote I agree is going to be true"business travel “will get crushed” thanks to the economic impact and workflow lessons of the pandemic.

“Many companies have learned for the first time that Zoom is highly effective,” he said. “And with finance budgets being slashed, the bar for what will be considered an essential in-person meeting will be much higher. For the first time ever, leisure travel will become the majority of hotel and airline profits.”

He also believes there won’t be nearly as many conferences.

“The conference industry will likely never recover,” he hypothesized. “Not only will be people not want to go to conferences during a recession and post-coronavirus, but conference organizers did not have pandemic insurance and most will go bankrupt because of this.”
Experts Predict How Coronavirus Will Change The Way We Travel

Galaril 04-30-2020 11:51 AM

Quote:

Originally Posted by panerd (Post 3278580)
I thought that was basically what a vaccine worked off of. I mean if the antibodies do nothing there cant be a vaccine right?


Yes true. Just going by what I have heard said by Fauci though a while ago where they are working on the vaccine but also that someone getting the disease may not provide much or any protection. I am not smart enough in the medical field to remotely understand the difference.

whomario 04-30-2020 12:44 PM

Vaccine vs Immunity: really can't come up with a way to explain it, but there is a massive difference. Essentially natural immunity depends on how the immune system reacts, a vaccine can be designed to make the immune system react in a specific way. There are various different ways, and while most vaccines actually use the virus in question in live or inactivated form, most proposed for Covid don't.

The questions right now is not if the antibodies "do something" but basically (i think).

1) there are enough of them created for all infected or maybe only those that get seriously ill
2) they stop it or only mitigate it (next time you get infected but not very sick)
3) how long the effects of protection last

It might well be that the first vaccine only creates immunity for a year or so and later ones last much longer of course.

albionmoonlight 04-30-2020 02:28 PM

One thing that this has taught me is that my 3rd grade teacher really skipped some details when she taught us how viruses and the immune system work.

RainMaker 04-30-2020 02:32 PM


albionmoonlight 04-30-2020 02:35 PM

Quote:

Originally Posted by RainMaker (Post 3278648)


That shit's gonna end up being the 270 To Win swing state map.

RainMaker 04-30-2020 02:35 PM

This also seems counter-intuitive to the purpose of FEMA.

https://www.cnn.com/2020/04/01/polit...ion/index.html

Quote:

Only a portion of the medical supplies being flown in by the Federal Emergency Management Agency from overseas are being allotted to critical hotspots prioritized by the agency and the Department of Health and Human Services. The rest will resupply the private market, where competition between states and the federal government has been a source of frustration for governors trying to shore up equipment to treat patients with coronavirus, according to multiple officials.

miami_fan 04-30-2020 02:41 PM

The Little League World Series has been cancelled for the first time since 1947.

thesloppy 04-30-2020 02:49 PM

Are they cooking the books in Florida?

Florida officials stop publishing medical examiners' coronavirus death data - Business Insider

albionmoonlight 04-30-2020 02:59 PM

Quote:

Originally Posted by thesloppy (Post 3278655)


One of the problems with solving this is that everyone agrees that more testing and more information is better. But information will make some people look bad, so there is an incentive to reduce testing and/or the public dissemination of information.

This seems like it would always be a problem on some level when you are talking about fixing things: (e.g., knowing in great detail how shitty the public schools are will better help us fix them, but the people in charge of that data don't want us know how shitty they've run the schools).

But the stark nature of this crisis puts the problem front and center.

Warhammer 04-30-2020 07:22 PM

Quote:

Originally Posted by Edward64 (Post 3278121)
Maybe it's how you define shortage, my guess is ... no shortage of meat at the source, the shortage is in the inability to process them and get them to the consumers.

BTW, anyone else notice there seems to be more SPAM commercials?


As someone that is now selling into the industry this is the issue. Our projects that were underway are continuing, if the project was waiting for funding or did not have the green light, they are on hold because the processors are trying to figure out how to keep running rather than trying to integrate new processes into their plant.

Not sure if it was here or somewhere else, if you know a local butcher in a lot of cases you can get meat cheap because the ranchers are trying to offload the mature animals so they do not need to maintain mature animals.

Last week, 2 million chickens were going to be destroyed in the Delmarva because there was no place to process the chickens. This is similar to what we were seeing with oil last week, we have plenty of the resource (in the case of oil there was no where to store it, here there is no place to process it so prices plunged).

BishopMVP 04-30-2020 08:14 PM

Not sure why they haven't announced anything, but Amazon is definitely setting up some sort of testing program. Ideally it will be voluntary & antigen/antibody tests instead of full testing, but there are rumors otherwise and not hard answer yet Amazon confirms COVID-19 testing program for employees in Fresno - Business Insider (And yes, I googled that because I literally saw a roped off corner with computers that had a screen saying employee Covid testing here at my Charlotte facility, so it is happening nationwide and it will be happening very soon is my guess.)

Amazon doing nationwide testing of that sort on a semi-regular basis would actually be amazing data for the country & many cities to use about community spread going forward as states re-open, and a decent data point about current spread (though many Amazon's probably have clusters & much higher exposure rates than GenPop). If they're testing for actually having Corona I'm a little less excited for that as a matter of public policy since it seems like it could be competing for tests vs medical personnel/older people who are at higher risk, but I'm still definitely down personally. (And hey, maybe Bezos has already scaled up company testing labs & designed Amazon's own test.)

JPhillips 04-30-2020 09:34 PM

Orange County, NY has 320 deaths with 8650 confirmed cases. If the death rate is @1% we're missing roughly 70-75% of cases.

The problem going forward is that in a county with a population of about 330,000, that means 90% or so still have no exposure and immunity.

PilotMan 04-30-2020 10:45 PM

Quote:

Originally Posted by JPhillips (Post 3278866)
Orange County, NY has 320 deaths with 8650 confirmed cases. If the death rate is @1% we're missing roughly 70-75% of cases.

The problem going forward is that in a county with a population of about 330,000, that means 90% or so still have no exposure and immunity.



Or more likely, you have the cases, but you don't have the tests to prove it. I'd wager that the death rate is far more stable and reliable that way, then the other way of trying to explain it.

CrimsonFox 05-01-2020 05:22 AM

Very sad story out of Wisconsin...

After Decades of Service, Five Nuns Die as Virus Sweeps Through Convent

These nursing homes and care centers are getting ravaged. There doesn't seem a way to save them :(

Edward64 05-01-2020 06:55 AM

Quote:

Originally Posted by Warhammer (Post 3278739)
Last week, 2 million chickens were going to be destroyed in the Delmarva because there was no place to process the chickens. This is similar to what we were seeing with oil last week, we have plenty of the resource (in the case of oil there was no where to store it, here there is no place to process it so prices plunged).


I know it's not this simple but in a perfect world we had enough capacity to give all the chickens etc. to food banks, homeless shelters etc. first before literally throwing them away.

Other options:

1) Give them to other countries if they want them
2) Give some to local farmers, residents etc. who want to increase their stock (you come pick it up)
3) Give them or sell them at cost to canning companies (e.g. Costco sells canned chicken)

sterlingice 05-01-2020 07:13 AM

Quote:

Originally Posted by BishopMVP (Post 3278760)
Not sure why they haven't announced anything, but Amazon is definitely setting up some sort of testing program. Ideally it will be voluntary & antigen/antibody tests instead of full testing, but there are rumors otherwise and not hard answer yet Amazon confirms COVID-19 testing program for employees in Fresno - Business Insider (And yes, I googled that because I literally saw a roped off corner with computers that had a screen saying employee Covid testing here at my Charlotte facility, so it is happening nationwide and it will be happening very soon is my guess.)

Amazon doing nationwide testing of that sort on a semi-regular basis would actually be amazing data for the country & many cities to use about community spread going forward as states re-open, and a decent data point about current spread (though many Amazon's probably have clusters & much higher exposure rates than GenPop). If they're testing for actually having Corona I'm a little less excited for that as a matter of public policy since it seems like it could be competing for tests vs medical personnel/older people who are at higher risk, but I'm still definitely down personally. (And hey, maybe Bezos has already scaled up company testing labs & designed Amazon's own test.)


Where I work has talked about how they've done more than 1% of the tests in Texas. That's great for us and our "customers" but it's absolutely embarrassing and dangerous for a state our size as we shouldn't account for anywhere near close to that.

SI

CrimsonFox 05-01-2020 07:25 AM

FUCK YEAH!!!!!!

YOU GO DEWINE! YOU TOTALLY ROCK!

Ohio's 'Stay Safe Ohio' order extended for another month


I will vote for this guy from now on.

grdawg 05-01-2020 10:38 AM

Quote:

Originally Posted by CrimsonFox (Post 3278931)
FUCK YEAH!!!!!!

YOU GO DEWINE! YOU TOTALLY ROCK!

Ohio's 'Stay Safe Ohio' order extended for another month


I will vote for this guy from now on.


That's great for your state, but with a lot of states reopening (including mine, Georgia) with very little restrictions are states going to start enforcing borders? If you continue to lock your state down, then you let in daily flights, travel from the non locked down states, how do you prevent the spread picking back up. I just think letting the states dictate this is problematic. I know a lot of states are looking at a regional reopening approach, but that doesn't address people coming in from other parts of the country.

One thing even with my state easing restrictions, a lot of the businesses that I go to are not opening yet. My daughters gymnastics place are planning on opening May 11th and sent out a survey to see how many would send their child or if they would want to continue doing the ZOOM classes. My wife asked me what I thought and I said 11 days from now could be a lot different so its hard to say. We answered ZOOM for now because I'd want to see where we stand then with all the reopening. My barber reopened last Friday and I desperately need a haircut, but I'm not going anywhere yet (still doing grocery pickup and delivery, not going into stores. Not sure when I will feel comfortable doing those things.

I guess the hope is that the lockdowns we just endured slowed the spread enough and that hospital capacity is ramped up that even by reopening, the system won't get overwhelmed. Also, got to hope with everyone wearing masks and just being more aware that there wouldn't be the need to go back to the complete lockdown.

ISiddiqui 05-01-2020 10:44 AM

Yeah, Georgia is a mess.

On the bright side, our Regional Director (as some of you know I work for the US Department of Labor) extended our telework until May 31. After our national office gave this vague we'll be on telework 'until further notice'. Seems like the federal government is also farming this out to the regions.

grdawg 05-01-2020 10:49 AM

Quote:

Originally Posted by ISiddiqui (Post 3279003)
Yeah, Georgia is a mess.



Do you know how good hospital capacity is at the moment? Do you expect things to get much worse now? I think at least from what I am seeing, a lot of business are being much more conservative and not listening to our moron governor.

ISiddiqui 05-01-2020 11:08 AM

Quote:

Originally Posted by grdawg (Post 3279007)
Do you know how good hospital capacity is at the moment? Do you expect things to get much worse now? I think at least from what I am seeing, a lot of business are being much more conservative and not listening to our moron governor.


Emory is still at ICU limits, but manageable. I can't speak for other hospitals. I think aside from Albany (which is in worse shape than Atlanta), hospital capacity should be ok for more rural areas - although those can easily get used up if people from Atlanta area hospitals have to be moved.

In most of Fulton and Dekalb counties most businesses seem to be remaining shut down or take out only. In some of the outer lying areas of those counties - North Fulton, East Dekalb, a few things are opening. In Avondale and Decatur, near where I live, there seems to be one business opening back up - Bad Daddy's Burger Bar.

ISiddiqui 05-01-2020 11:12 AM

Well I just texted my friend at Emory. He said so many providers are getting sick that they are putting their hospitalists in the ICU to make ends meet. Fun.

lungs 05-01-2020 11:24 AM

Quote:

Originally Posted by Edward64 (Post 3278923)
I know it's not this simple but in a perfect world we had enough capacity to give all the chickens etc. to food banks, homeless shelters etc. first before literally throwing them away.

Other options:

1) Give them to other countries if they want them
2) Give some to local farmers, residents etc. who want to increase their stock (you come pick it up)
3) Give them or sell them at cost to canning companies (e.g. Costco sells canned chicken)


None of those three options are feasible when there is nobody to:
1) Kill the chickens
2) Pluck feathers
3) Gut them
4) Cut off the waste parts

Secondly, if chickens can’t be processed, why would farmers want more of them? Poultry is mostly a vertically integrated thing anyway so there aren’t lots of independent chicken farmers out there to pick up excess chickens and then put feed ($$$) into them for no gain and hope there is a market for them later. If a chicken isn’t butchered at a young age, the meat isn’t fit for much besides soup anyway.

miked 05-01-2020 11:30 AM

Quote:

Originally Posted by ISiddiqui (Post 3279026)
Well I just texted my friend at Emory. He said so many providers are getting sick that they are putting their hospitalists in the ICU to make ends meet. Fun.


We've been covering from different departments for a few weeks. Housing on campus is now for sick nurses/doctors/etc. In a few weeks we should see another spike.

Lathum 05-01-2020 01:16 PM

Quote:

Originally Posted by lungs (Post 3279030)
None of those three options are feasible when there is nobody to:
1) Kill the chickens
2) Pluck feathers
3) Gut them
4) Cut off the waste parts

Secondly, if chickens can’t be processed, why would farmers want more of them? Poultry is mostly a vertically integrated thing anyway so there aren’t lots of independent chicken farmers out there to pick up excess chickens and then put feed ($$$) into them for no gain and hope there is a market for them later. If a chicken isn’t butchered at a young age, the meat isn’t fit for much besides soup anyway.


Is this work typically done by illegals or people with questionable citizenship?

Warhammer 05-01-2020 01:37 PM

Quote:

Originally Posted by lungs (Post 3279030)
None of those three options are feasible when there is nobody to:
1) Kill the chickens
2) Pluck feathers
3) Gut them
4) Cut off the waste parts

Secondly, if chickens can’t be processed, why would farmers want more of them? Poultry is mostly a vertically integrated thing anyway so there aren’t lots of independent chicken farmers out there to pick up excess chickens and then put feed ($$$) into them for no gain and hope there is a market for them later. If a chicken isn’t butchered at a young age, the meat isn’t fit for much besides soup anyway.


This, and the same goes for pigs and cows (although there are local butchers and more local farmers for these in various areas. We normally get 1/4 to 1/2 of a cow every year from a local farmer if he has excess).

Warhammer 05-01-2020 01:38 PM

Quote:

Originally Posted by Lathum (Post 3279065)
Is this work typically done by illegals or people with questionable citizenship?


Depends upon where you are and who the company is. Further north, not super likely. If it is in Texas, it would not surprise me in the least.

spleen1015 05-01-2020 01:52 PM

Indiana is going to reopen in a staged approach.

I think I'll just stay home.

albionmoonlight 05-01-2020 02:32 PM

Tests in recovered patients found false positives, not reinfections, experts say

Previous reports of possible re-infections look to have instead been caused by body continuing to shed virus.

That won't get headlines, but it's very very very good news (or, maybe more accurately, a refutation of something that would have been horrible news).

sterlingice 05-01-2020 02:33 PM

I really hope that's true

SI

RainMaker 05-01-2020 02:42 PM

Quote:

Originally Posted by ISiddiqui (Post 3279019)
In most of Fulton and Dekalb counties most businesses seem to be remaining shut down or take out only. In some of the outer lying areas of those counties - North Fulton, East Dekalb, a few things are opening. In Avondale and Decatur, near where I live, there seems to be one business opening back up - Bad Daddy's Burger Bar.


I still think opening up is a bottom up thing more than a top down issue. The states can scream about opening for business but as long as the virus is around, people are going to stay home. I think I saw some video of people going to restaurants in Georgia, but it was small. Barbers and hair salons seemed busy but that's likely because so many people have gone without for a couple months.

The only way you get the economy back is by controlling or eliminating the virus. We don't seem to have any desire to control it and I think their games with testing and reporting is just going to hurt the recovery.

Kind of like what's happening in Brazil. They kept everything open and claimed it's all good. But now that the bodies are piling up, everyone is pissed and staying home.

rjolley 05-01-2020 02:42 PM

I like California's plan that was laid out recently: Gavin Newsom on Twitter: "CA is flattening the curve, but the reality is #COVID19 is not going away soon.

Our re-opening must be gradual, guided by public health and science, and will be done in the following STAGES:"


4 stages. Appears thought out and reasonable. No dates, but that's ok. There have been other notifications that it'll be based on better testing, data, and guidance from various experts.

At least it's a thought out plan.

Also, I like the state's COVID-19 website: California Coronavirus COVID-19 Response

whomario 05-01-2020 02:43 PM

Because it angers me people do this and political leadership fails to adress it.:
The March idea that the curve is sufficiently flat juuuust below the theoretical capacity (beds/ventilators) is simply bullshit given what we now know and what it looks like in the field.
Covid19 needs a ton of space and personnel (all of whome can not switch back and forth easily) per patient, meaning 20% of possible patients being covid takes away a lot more than 20% capacity.

Quote:

Originally Posted by sterlingice (Post 3279104)
I really hope that's true

SI


Had been suspected to be the case all along, so that basically confirms what scientific 'common sense' figured so i am pretty certain this is now put to rest.

RainMaker 05-01-2020 02:46 PM

Quote:

Originally Posted by Warhammer (Post 3278739)
As someone that is now selling into the industry this is the issue. Our projects that were underway are continuing, if the project was waiting for funding or did not have the green light, they are on hold because the processors are trying to figure out how to keep running rather than trying to integrate new processes into their plant.

Not sure if it was here or somewhere else, if you know a local butcher in a lot of cases you can get meat cheap because the ranchers are trying to offload the mature animals so they do not need to maintain mature animals.

Last week, 2 million chickens were going to be destroyed in the Delmarva because there was no place to process the chickens. This is similar to what we were seeing with oil last week, we have plenty of the resource (in the case of oil there was no where to store it, here there is no place to process it so prices plunged).


Processing capacity is down but it's not stopped. There are still plenty of companies that have done things right and are still open for business.

The issue with Tyson and Smithfield is they were negligent from the start. They're throwing out scary stuff to get the feds to eliminate the billion or so in liabilities they are likely on the hook for from dead employees (and their families). Smithfield was offering $500 to employees who made every shift which is as moronic as it gets.

Like I mentioned before, my brother works in the field. The factories at his company are working at fully capacity. But they offer paid sick leave, PPE, have re-done the layout to allow for spacing, and take temperature at the door. When they had a few cases at a factory, they closed it down for a few days to sanitize everything and then opened on limited basis with proper spacing. Now it's back to full operation.

If there is a shortage, it's because Smithfield and Tyson was negligent.

sterlingice 05-01-2020 03:27 PM

Quote:

Originally Posted by whomario (Post 3279117)
Had been suspected to be the case all along, so that basically confirms what scientific 'common sense' figured so i am pretty certain this is now put to rest.


Yes, but with so many unknowns with this virus, it's nice to get some data in the confirmation column that fits into the "good news" category.

SI

lungs 05-01-2020 03:48 PM

Quote:

Originally Posted by Lathum (Post 3279065)
Is this work typically done by illegals or people with questionable citizenship?


From my experience, probably. Even in the north. Go to a packing plant in Green Bay and you're going to see mostly Latinos. Deduce what you want about their legality but as somebody well experienced in hiring from the Latino population in Wisconsin, I'd say the odds are pretty high most are undocumented.


Quote:

Originally Posted by Warhammer (Post 3279076)
This, and the same goes for pigs and cows (although there are local butchers and more local farmers for these in various areas. We normally get 1/4 to 1/2 of a cow every year from a local farmer if he has excess).


I thought my Wagyu beef from the last steer I ever owned was just that, the last of it. Then I just found out yesterday that the guy I gave my last four steers still had the remaining three. So I'm getting another Wagyu and he's getting the other two. Wagyu.... best meat ever

lungs 05-01-2020 03:55 PM

Quote:

Originally Posted by RainMaker (Post 3279118)
If there is a shortage, it's because Smithfield and Tyson was negligent.


From what I saw, you can add Brazilian owned JBS to the list of negligent companies. Of course JBS is just going to bring Brazilian beef in, so I truly doubt a shortage is on the horizon.

Funny story, when I had 150 milking cows left, I took bids from JBS and American Dressed Meats to buy them. JBS sent out an extremely attractive young lady in the attempt to compensate for their bid coming in a few cents short of Dressed Meats. The trump card for Dressed Meats was that I knew their trucker, a fellow named Smoothy. I knew we'd have those cows out of there in no time, working with Smoothy. So the better price and better trucker won out.

Edward64 05-01-2020 04:07 PM

Kudos to Gilead for (seemingly) doing the right thing without regard to profits. What they don't make in profits, I hope they make in recognition & goodwill.

Now let's hope the drug really is significantly effective.

https://www.marketwatch.com/story/ho...?mod=home-page
Quote:

The Food and Drug Administration on Friday granted an emergency use authorization to Gilead Sciences Inc.’s remdesivir, a decade-old experimental therapy first tested on Ebola disease patients, as a COVID-19 treatment.
:
:
“Under the emergency-use authorization, one could charge for the product,” CEO O’Day told investors on the earnings call. “We made a decision, as you know, to donate 1.5 million vials, which is the entirety of our supply through the early summer.” The vials encompass 140,000 10-day treatment courses. O’Day later said during the call that donating the investigational therapy “is the right thing to do at this time.”

Analysts later stressed their concerns about the company’s lack of clarity about revenue eneration for a drug brought to market under emergency powers during a global pandemic with huge public health implications.

CrimsonFox 05-01-2020 09:06 PM



And if you rearrange the letters of CORONA you get RACOON (which is very very close)

tarcone 05-01-2020 09:09 PM

I prefer Trash Panda

IlliniCub 05-01-2020 10:39 PM

Quote:

Originally Posted by Edward64 (Post 3279154)
Kudos to Gilead for (seemingly) doing the right thing without regard to profits. What they don't make in profits, I hope they make in recognition & goodwill.

Now let's hope the drug really is significantly effective.

https://www.marketwatch.com/story/ho...?mod=home-page

From what I've read so far it's looking more like a building block than a knock out punch. Kind of like the first hiv drugs. Definite step forward but not THE step most likely. Still any help we can get we'll welcome. Also it takes a long time to produce and manufacture I guess as well.

Galaril 05-01-2020 10:44 PM

Quote:

Originally Posted by IlliniCub (Post 3279211)
From what I've read so far it's looking more like a building block than a knock out punch. Kind of like the first hiv drugs. Definite step forward but not THE step most likely. Still any help we can get we'll welcome. Also it takes a long time to produce and manufacture I guess as well.


Yeah said December before they would have 500000 doses so not sure it is anything more than help for the most sick now and to come.

stevew 05-01-2020 11:36 PM

I read some article from a chemist(can’t find link) and it basically said that this drug is a complete bear to make at this point. All kinds of complicated reactions. Lots of waste to get to purity.

stevew 05-01-2020 11:39 PM

OMG! We Made One Gram of Remdesivir! | American Council on Science and Health

RainMaker 05-02-2020 01:37 AM

Quote:

Originally Posted by Edward64 (Post 3279154)
Kudos to Gilead for (seemingly) doing the right thing without regard to profits. What they don't make in profits, I hope they make in recognition & goodwill.

Now let's hope the drug really is significantly effective.

https://www.marketwatch.com/story/ho...?mod=home-page


Your tax dollars paid for the research at UAB to develop it. It is the least they could do.

Edward64 05-02-2020 05:27 AM

Quote:

Originally Posted by CrimsonFox (Post 3279206)


And if you rearrange the letters of CORONA you get RACOON (which is very very close)


Funny, I like this!

Edward64 05-02-2020 05:41 AM

Quote:

Originally Posted by stevew (Post 3279226)


Thanks. I read the first couple paragraphs and then my stopped ... but appreciate the link. He had another post which talked about the effectiveness ...

Remdesivir 1st Controlled Trial Is No Cause For Celebration | American Council on Science and Health
Quote:

We now have data from the first trial and I'm more than a little disappointed. Remdesivir is effective in treating COVID-19 but it isn't anything close to a wonder drug. Let's call it a good start. More on that later.
:
:
To put this in perspective let's consider the therapies for two known RNA virus medications, Tamiflu and Sovaldi. Tamiflu is marginally helpful for treating influenza, but only when taken early in the infection. Even so, it knocks one day off the time until symptoms cease – from seven days to six. By contrast, Sovaldi, a nucleoside inhibitor like remdesivir, became the first successful direct-acting antiviral drug to cure hepatitis C infections (1). Sovaldi was a game-changer. Remdesivir is not. Remdesivir is more like Tamiflu than Sovaldi.

Here are the data that have been released so far.
  • Patients who got remdesivir recovered 31% faster (11 days vs 15 days) than those who got a placebo.
  • There was a relatively modest improvement in survival for the drug-treated group (8.0% mortality rate) compared to those who received a placebo (11.6%), but these results were just short of statistical significance (p = 0.059). This is probably real nonetheless.
Why am I so pessimistic? Because as things stand now, remdesivir will have little or no impact on our (new) daily lives – social distancing, mask use, and fear... Most likely it will be just a better option for people who are already ill and have been hospitalized by COVID-19, and only by four days. Don't get me wrong; the decreased hospital stay (and the lower mortality rate, should the numbers hold up) is not insignificant for those who are already ill enough to be hospitalized. I just don't see any way that remdesivir will keep people out of the hospital at this time, so in this sense, the drug has failed.
:
:
Unfortunately, based on this first trial, it is doubtful that remdesivir will be the "magic pill" people have been hoping for. Remdesivir is not something people will be able to swallow at the first sign of COVID disease and feel better.

Great news on getting patients out of the hospital quicker but somewhat disappointed in the small reduction in mortality.

I do disagree with the last bolded statement. Although it may not keep people out of hospital, helping them recover quicker helps healthcare workers, hospital capacity, available equipment & medicines etc. and future patients.

tarcone 05-02-2020 10:37 AM

There was a guy in St Louis county that had the virus and was experiencing organ failure and the doctors gave him a 20% chance to live. He got the plasma treatment and started recovering almost immediately. He will be going home next week after being in the hospital for 5 weeks.

First COVID-19 patient in St. Louis-area to receive experimental treatment makes remarkable recovery | FOX2now.com

CrimsonFox 05-02-2020 11:02 AM

wait...they gave people that were IN THE HOSPITAL for COVID-19....a PLACEBO?!?!?

NobodyHere 05-02-2020 12:01 PM

Quote:

Originally Posted by CrimsonFox (Post 3279260)
wait...they gave people that were IN THE HOSPITAL for COVID-19....a PLACEBO?!?!?


Don't they have to when testing a drug?

QuikSand 05-02-2020 12:08 PM

Quote:

Originally Posted by NobodyHere (Post 3279261)
Don't they have to when testing a drug?


Yes, of course, nothing to see here. If amidst a trial there seems to be clear evidence of the treatment being effective and important, it's at that point where an ethical matter arises. But not at the outset for a completely unknown treatment.

Warhammer 05-02-2020 12:45 PM

Quote:

Originally Posted by RainMaker (Post 3279118)
Processing capacity is down but it's not stopped. There are still plenty of companies that have done things right and are still open for business.

The issue with Tyson and Smithfield is they were negligent from the start. They're throwing out scary stuff to get the feds to eliminate the billion or so in liabilities they are likely on the hook for from dead employees (and their families). Smithfield was offering $500 to employees who made every shift which is as moronic as it gets.

Like I mentioned before, my brother works in the field. The factories at his company are working at fully capacity. But they offer paid sick leave, PPE, have re-done the layout to allow for spacing, and take temperature at the door. When they had a few cases at a factory, they closed it down for a few days to sanitize everything and then opened on limited basis with proper spacing. Now it's back to full operation.

If there is a shortage, it's because Smithfield and Tyson was negligent.


Much of it depends upon the management of the plant. Tyson I’ve seen well run and poorly run. Smithfield, they are pretty poor all the way around.

As an example we’re working on a few expansions at few facilities, at one everything with the project has been above board, there have been zero games on the sourcing side, I am fully confident the system will work. At another facility, they are trying to shoestring the project, simple stuff they are arguing with the contractor about having to pay for (crap like can’t liquid magically go from one tank to another). I have little faith it will be a good installation.

The big problem, we (myself and the 40 yr industry vet I am eventually taking over from) were discussing with my company’s management yesterday and explaining how the plants work. They were floored they weren’t more automated. Essentially, most plants you have people working should to shoulder next to each other on the line. Most are looking for one type of cut to make or inspecting for one type of blemish (varies a bit by plant). The reason is the different body shape, size, etc., from animal to animal. This is different from the vegetable industry where everything is more consistent and you can have machines do much of the processing.

Anyway, getting back to the meat plants, depending upon the age of the plant, you may not have a way to put shields or barriers next to people. It’s not as simple as just installing them because of where the drains, chutes, and other entry/disposal points are on the line. At some plants where you have floor penetrations for the waste chutes, etc., it is not just a simple matter of moving it because you’d need a contractor to come in and make the change.

Not to mention shield protect you from the person next to you, not the person across from you. With some of the processing being done a front shield does not work well either, sometimes you need more room to work than a shield allows.

stevew 05-02-2020 01:14 PM

FIL had to have an emergency pacemaker installed. Thank god they’re just sending him home instead of farming him out to a rehab center rn.

whomario 05-02-2020 01:21 PM

Quote:

Originally Posted by CrimsonFox (Post 3279260)
wait...they gave people that were IN THE HOSPITAL for COVID-19....a PLACEBO?!?!?


Remember that it is equally morally iffy to give it to people in the first place, especially in cases hospitalised but not/not yet in life threatening condidition that very likely would be just fine without the drug. Which you also need to do since you need to find not only if it helps but at what stage it helps most. And by design an antiviral drug needs to be administered early(ish), especially considering that many patients have their viral load go down after less than 1 week of symptoms.
Which is why the "what do you have to loose" rhetoric by Trump was so insane.

There is a reason why under normal circumstances these things take so much longer than they do right now. It is by nature extremely morally ambigous/challenging even when not played at the high stakes table like now ...

whomario 05-02-2020 01:27 PM

At the end of the day there won't be that one drug/treatment, this disease is way too varied for that. You have classic respiratory strains/pneumonia, but you also have damage to the heart, kidneys, blood vessels and blood clotting leading to strokes.

NobodyHere 05-02-2020 01:32 PM

....


Post moved to Trump thread

whomario 05-02-2020 02:11 PM

Meanwhile, he who casts the first stone etc ... (As far as doing Experiments on Viruses)

Gain-of-function research: Why labs should stop making viruses deadlier - Vox

as an aside : why do you need to put it as a percentage when talking about 17 agencies. So between 11.9 and 12.75 agencies believe it ? ;)

Unless they do find a smoking gun, I'd lean towards believing the people that study this stuff.

EDIT:
Quote:

The source said that the agencies have come down to two potential origins for the accident - animal-human transmission, or a mistake in the lab

Aren't those the only 2 conceivable options ?

Warhammer 05-02-2020 05:15 PM

Quote:

Originally Posted by whomario (Post 3279273)
Meanwhile, he who casts the first stone etc ... (As far as doing Experiments on Viruses)

Gain-of-function research: Why labs should stop making viruses deadlier - Vox

as an aside : why do you need to put it as a percentage when talking about 17 agencies. So between 11.9 and 12.75 agencies believe it ? ;)

Unless they do find a smoking gun, I'd lean towards believing the people that study this stuff.

EDIT:

Aren't those the only 2 conceivable options ?


You do have mutation of another strain of a coronavirus already in humans.

Thomkal 05-02-2020 08:01 PM

Fantasy Author Brandon Sanderson wanted to do something to help ease the boredom of those stuck at home during this pandemic. Took a while for his publishing company Tor to get it organized, but you can sign up for Tor's Ebook club and on Monday May 4th they will send you an e-book version of The Way of Kings, the first book in his Stormlight Archive. That should keep you busy for a while. :)

On May 4 We’re Offering a Free eBook of The Way of Kings by Brandon Sanderson | Tor.com

CrimsonFox 05-02-2020 08:04 PM

Quote:

Originally Posted by QuikSand (Post 3279262)
Yes, of course, nothing to see here. If amidst a trial there seems to be clear evidence of the treatment being effective and important, it's at that point where an ethical matter arises. But not at the outset for a completely unknown treatment.


yeah I know that's how science works...but to really give it the ole sciencey try you have to give them nothing else either.

I don't think this is the time to be messing around.

miked 05-02-2020 08:23 PM

Quote:

Originally Posted by CrimsonFox (Post 3279260)
wait...they gave people that were IN THE HOSPITAL for COVID-19....a PLACEBO?!?!?


The good news is that if it is incredibly effective, they can halt the trial early and get approval.

albionmoonlight 05-02-2020 09:13 PM

Based on the anecdotes on social media of people treating this weekend as a "Corona is over; let's all go to parks and stores and breath on each other" party, I fear that the second wave will be coming.

This isn't a red/blue thing either. Apparently, it's everyone. It seems that human beings in 2020 can stand to be inconvenienced for about 200 hours or so before they decide it's not worth it.

ISiddiqui 05-02-2020 10:11 PM

Yeah, the pictures of Piedmont Park in Atlanta was terrifying. No one wearing a mask, no social distancing. People really are acting like it's all over.


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